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BestCrosswords.com - "Life Lesson" by AVXWords on 1/26/2006 [moderate]
Across 1- Each; 6- Simile center; 9- They may be let out in relief; 14- Drive in Los Angeles; 15- Trail; 16- Square in Manhattan; 17- Beginning of a hypothesis proposed by me in 51-Across; 19- Assassin in black; 20- Explorer Hernando De ___; 21- Center of Anytown, USA; 23- Drench; 24- Continuation of the hypothesis; 27- Force member; 30- 1300 hours; 31- Billy of "Titanic"; 32- Insert sign; 34- Unagi, at a sushi bar; 35- Moonroof alternative; 39- "Elements" of the hypothesis, letter-wise; 43- "The Godfather" author; 44- NASDAQ debut; 45- Patronage; 46- It's saved for a rainy day; 48- Be off; 50- Cooperative farm worker; 51- See 17- and 24-Across; 56- Bilbo's portrayer; 57- Like Jay-Z and Beyoncé; 58- Manager's company?; 62- Abandon; 64- Given this puzzle's theme, conclusion about the hypothesis; 66- It begins un a?o; 67- Metric base; 68- Bold poker bet; 69- Not on deck; 70- Tokyo, during a shogunate; 71- First word after a sneeze, often;   Down 1- MFA part; 2- Hostess treat; 3- Tweak; 4- Man of morals; 5- "Simpsons" cry; 6- Historically-disputed French region; 7- City dept. concerned with trash; 8- Struggles, as over a decision; 9- Beach pick-up; 10- Pasta suffix; 11- Infomercial knife; 12- Fast-disappearing roadside eateries; 13- Harry Potter's professor; 18- To ___ (everyone); 22- Dragonlike; 25- Hindi bread; 26- Do not disturb; 27- USSR, in Cyrillic; 28- Pearl Harbor's island; 29- W, in tabloids; 33- Overdo it; 34- 70's rock band from Birmingham, for short; 36- Frat party outfit; 37- Lena of "Alias"; 38- "Yoo-hoo!"; 40- Approximately; 41- It may get worked up; 42- Candy name; 47- "I'll say!"; 48- Weird weather cause; 49- Tattered attire; 51- Half an LP; 52- Captain Queeg?s ship; 53- Processor producer; 54- Given a ticket; 55- Buy time; 59- Glamour rival; 60- Thrift store tag; 61- Department with ties; 63- ___-Magnon; 65- Part of a "Queer Eye" nickname;