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BestCrosswords.com - "Fly-by-Nights (10017)" by Gareth Bain on 4/21/2010 [moderate]
Across 1- Home to the World Heritage Site "Piazza del Duomo"; 5- ___-di-dah; 8- Buffalo iceman; 13- "The old ___" (sin); 14- Alternative to tapioca; 15- Signs on; 16- Utah's state flower; 17- Putin's veto; 18- Farewell to one's amigos; 19- Put in some time at the fleamarket; 22- In the style of; 23- Alley ___; 24- Tiny handful; 25- Active ingredient in cannabis; 28- Burlesque star with famous memoirs; 31- Events for the "bull-ish"; 34- ___ Lingus; 35- River to the Arctic Ocean; 36- Koppie flora; 37- Beta-max alternative; 38- Perceives via the cochlea; 39- Darkroom pix; 40- Duran Duran girl; 41- Bind hand and foot; 42- South Korea or Singapore in the 1990s, e.g.; 45- ___-Fi; 46- Tolkien being; 47- Be in hock; 48- Successor to GWB; 51- Hadrian's adopter; 55- 2004 Usher / Alicia Keys duet; 57- Cognizant; 58- Three-dimensional figure with one vertex; 59- Yachts, e.g.; 60- Vientiane's country; 61- Disney film of 1982; 62- Zero, quaintly; 63- ___ Arbor; 64- Anti-___ brakes;   Down 1- Turkish ruler; 2- Standard; 3- Amy Tan title cat; 4- Run ___ (go wild); 5- Basketball gimmes; 6- Golden-___; 7- Starts, as a car thief; 8- ___ bin (container for medical waste); 9- ___-de-camp; 10- React angrily; 11- ___ Speedwagon; 12- Bend shape; 14- Is a nosy neighbor; 20- Vacillates; 21- Cupid; 26- Painter Matisse or Toulouse-Lautrec; 27- ___ and desist; 28- Honking flock; 29- Houyhnhm's counterpart; 30- Adonais, e.g.; 31- Incendiary outbursts; 32- ___ acid (glyceryl ester); 33- Restaurant orts; 37- 1906 Phonograph; 38- ___ Jay Simpson; 40- Painter Magritte; 41- Instruction manuals; 43- Forum repeat; 44- Kaspersky alternative; 48- One-named singer whose surname is Guðmundsdóttir; 49- Hoa Lo Prison, aka The ___ Hilton; 50- Upturned; 52- Insect kinds of which start 19-, 28-, 42-, and 51A; 53- Ill-fated son of Judah; 54- Book that chronicles the martyrdom of St. Stephen; 55- CEO's degree, often; 56- U, written out;